Search results for "Plasma cell membrane"

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Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.

2015

BACKGROUND: Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the theory that Hsp60 has potential as a biomarker as well as a therapeutic target in patients with large bowel cancer. METHODS: The authors studied a population of 97 subjects, including patients and controls. Immunomorphology, Western blot analysis, and quantitative real-time polymerase chain reaction were performed on tissue specimens. Exosomes were isolated from blood and characterized by electr…

MaleCancer ResearchMacrophageBlotting WesternNatural killer cellEnzyme-Linked Immunosorbent AssayAdenocarcinomaExosomesReal-Time Polymerase Chain ReactionMitochondrial ProteinsHeat shock protein 60 (Hsp60)Biomarkers TumorHumansColon adenocarcinomaAgedColon adenocarcinoma; Exosomes; Heat shock protein 60 (Hsp60); Macrophages; Natural killer cells; Plasma cell membrane; Theranostics; Cancer Research; OncologyAged 80 and overPlasma cell membraneChaperonin 60Middle AgedImmunohistochemistryExosomeTheranosticOncologyColonic NeoplasmsFemaleCancer
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